AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs12344615
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 Polymorphism: rs12344615 (UBQ_8i)
 Gene: UBQLN1   Entrez Gene    View on PDGene
 Protein: ubiquilin 1   ProteinLink
 Chromosome: 9   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 12 September 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   C-Allele
(frequency)		 T-Allele
(frequency)		 C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian 11 AD
CTR		 0.19
0.19		 0.81
0.82		 156 (0.036)
343 (0.035)		 1352 (0.312)
2897 (0.299)		 2824 (0.652)
6450 (0.666)
 Asian 1 AD
CTR		 0.00
0.00		 1.00
1.00		 0 (0.000)
0 (0.000)		 0 (0.000)
0 (0.000)		 91 (1.000)
96 (1.000)
Total 12 AD
CTR		 0.19
0.18		 0.81
0.82		 156 (0.035)
343 (0.035)		 1352 (0.306)
2897 (0.296)		 2915 (0.659)
6546 (0.669)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs12344615 (UBQ_8i)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs10868038
rs11140213
rs12345514 (promoter)
rs1333862
rs2780995
rs2781002
rs2781003
rs2781004
rs2811925
rs3814507
rs4877797
rs7866234 (UBQ 10e)
rs944947

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Top Results Details
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2. BIN1
3. CLU
4. ABCA7
5. CR1
6. PICALM
7. MS4A6A
8. CD33
9. MS4A4E
10. CD2AP
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.