AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs5930
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 Polymorphism: rs5930 (exon 10)
 Gene: LDLR  (FH; FHC)  Entrez Gene    View on ALSGene
 Protein: low density lipoprotein receptor   ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   A-Allele
(frequency)		 G-Allele
(frequency)		 A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian 4 AD
CTR		 0.39
0.43		 0.61
0.58		 83 (0.138)
155 (0.173)		 299 (0.496)
453 (0.504)		 221 (0.367)
290 (0.323)
Total 4 AD
CTR		 0.39
no data available		 0.61
no data available		 83 (0.138)
155 (0)		 299 (0.496)
(0)		 221 (0.367)
290 (0)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs5930 (exon 10)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

Msp1 (exon 18)
rs11668477
rs12983082
rs1433099
rs2228671
rs2738444
rs5927 (exon 15)

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Top Results Details
1. APOE_e2/3/4
2. BIN1
3. CLU
4. ABCA7
5. CR1
6. PICALM
7. MS4A6A
8. CD33
9. MS4A4E
10. CD2AP
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.