AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs17269348
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 Polymorphism: rs17269348
 Gene: ADAM10  (kuz; HsT18717; kuzbanian; MADM)  Entrez Gene
 Protein: a disintegrin and metalloproteinase domain 10   ProteinLink
 Chromosome: 15   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 4 AD
CTR
0.13
0.12
0.87
0.88
70 (0.018)
84 (0.012)
901 (0.229)
1470 (0.208)
2957 (0.753)
5500 (0.780)
Total 4 AD
CTR
0.13
0.12
0.87
0.88
70 (0.018)
84 (0.012)
901 (0.229)
1470 (0.208)
2957 (0.753)
5500 (0.780)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs17269348

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

C-348T
del-927ins
rs10518984
rs10851639
rs11071385
rs11071386
rs11071392
rs11071393
rs11071397
rs11639204
rs11857405
rs12324536
rs12437457
rs12438487
rs12439231
rs12441313
rs12591291
rs12594872
rs12901512
rs12913383
rs1427280
rs1427281
rs1427282
rs16940472
rs16940571
rs16940602
rs16940629
rs16940651
rs16940712
rs16940751
rs16940810
rs16953389
rs17190678
rs17269341
rs17301795
rs1869133
rs1869135
rs1968687
rs1968689
rs1979178
rs2052805
rs2305421
rs2414598
rs2414599
rs2414607
rs2657125
rs347117
rs3751542
rs383902
rs4238331
rs442495
rs4775083
rs4775085 (rs7402779)
rs4775086
rs4775096
rs514049 (G-630T)
rs593742
rs605928
rs6494025
rs6494030
rs6494031
rs6494036
rs6494038
rs653765 (A-279G)
rs664936
rs690
rs714696
rs7161889
rs7163733
rs7164844
rs7165035
rs7166076
rs7166325
rs7171589
rs7174210
rs7174386
rs7179747
rs7180130
rs8026668
rs8028759
rs8029805
rs8035006
rs8036097
rs9302203

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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.