AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs2233678
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 Polymorphism: rs2233678 (-842G/C)
 Gene: PIN1  (DOD; UBL5)  Entrez Gene
 Protein: protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting  (prolyl isomerase)  ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
G-Allele
(frequency)
C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian 4 AD
CTR
0.11
0.10
0.89
0.90
21 (0.013)
13 (0.009)
308 (0.193)
273 (0.186)
1268 (0.794)
1178 (0.805)
Total 4 AD
CTR
0.11
0.10
0.89
0.90
21 (0.013)
13 (0.009)
308 (0.193)
273 (0.186)
1268 (0.794)
1178 (0.805)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs2233678 (-842G/C)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

c+370G>T (Ala123Ser)
g-505 ins/del
rs1077220
rs2010457
rs2233682
rs2233683
rs2287838
rs2287839
rs4804459
rs889162

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AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.