AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs1799900
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 Polymorphism: rs1799900 (intron 13)
 Gene: DLST  (DLTS)  Entrez Gene    View on PDGene
 Protein: dihydrolipoamide S-succinyltransferase   ProteinLink
 Chromosome: 14   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
C-Allele
(frequency)
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian 3 AD
CTR
0.54
0.57
0.46
0.43
120 (0.278)
151 (0.326)
226 (0.523)
223 (0.482)
86 (0.199)
89 (0.192)
 Asian 3 AD
CTR
0.54
0.51
0.47
0.49
180 (0.293)
262 (0.256)
298 (0.485)
512 (0.500)
137 (0.223)
250 (0.244)
Total 6 AD
CTR
0.54
0.53
0.46
0.48
300 (0.287)
413 (0.278)
524 (0.500)
735 (0.494)
223 (0.213)
339 (0.228)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1799900 (intron 13)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

Exon 4
rs1971689
rs2159905
rs3213716
rs3213717
rs8185

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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.