AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs10997691
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 Polymorphism: rs10997691 (SNP1)
 Gene: VR22  (CTNNA3; MGC26194)  Entrez Gene
 Protein: catenin (cadherin-associated protein), alpha 3  (alpha-catenin-like protein)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples		   C-Allele
(frequency)		 T-Allele
(frequency)		 C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian 4 AD
CTR		 0.14
0.11		 0.87
0.89		 17 (0.028)
10 (0.013)		 128 (0.213)
143 (0.190)		 455 (0.758)
599 (0.797)
Total 4 AD
CTR		 0.14
0.11		 0.87
0.89		 17 (0.028)
10 (0.013)		 128 (0.213)
143 (0.190)		 455 (0.758)
599 (0.797)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs10997691 (SNP1)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs10822890
rs10996886
rs10997307
rs12258078
rs12357560 (4783)
rs1786927
rs2105702
rs2126750
rs2306402
rs2394287
rs2441718
rs2456737
rs3096244
rs3750863
rs4459178
rs4548513 (Ser596Asn)
rs6480140
rs7074454
rs713250
rs7909676
rs7911820 (4825)
rs997225

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Top Results Details
1. APOE_e2/3/4
2. BIN1
3. CLU
4. ABCA7
5. CR1
6. PICALM
7. MS4A6A
8. CD33
9. MS4A4E
10. CD2AP
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
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An up-to-date collection of all published genetic association studies.