AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs8106922
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 Polymorphism: rs8106922
 Gene: TOMM40  (TOM40; PEREC1; C19orf1; PER-EC1; D19S1177E)  Entrez Gene    View on MSGene
 Protein: translocase of outer mitochondrial membrane 40 homolog (yeast)   ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 7 AD
CTR
0.30
0.40
0.70
0.60
684 (0.091)
1884 (0.163)
3176 (0.424)
5462 (0.472)
3623 (0.484)
4222 (0.365)
Total 7 AD
CTR
0.30
0.40
0.70
0.60
684 (0.091)
1884 (0.163)
3176 (0.424)
5462 (0.472)
3623 (0.484)
4222 (0.365)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs8106922

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

19AyD0326
rs10119
rs1038025
rs1038026
rs10524523 (polyT VNTR)
rs11556505
rs1160983
rs1160985
rs1305062
rs157582
rs157583
rs157584
rs157585
rs157587
rs157588
rs157590
rs2075649
rs283817
rs34215622
rs34878901
rs394819
rs405697
rs434132
rs446037
rs573199
rs7256173
rs7259620
rs741780
rs760136
TOMM40_novel

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AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.