AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs8192708
Back Search Methods Disclaimer Credits
 Polymorphism: rs8192708
 Gene: PCK1  (PEPCK1; PEPCKC)  Entrez Gene    View on SZGene
 Protein: phosphoenolpyruvate carboxykinase 1 (soluble)  (cytosolic phosphoenolpyruvate carboxykinase 1; PEP carboxykinase)  ProteinLink
 Chromosome: 20   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 8 AD
CTR
0.13
0.12
0.87
0.88
103 (0.029)
103 (0.027)
708 (0.203)
721 (0.192)
2684 (0.768)
2923 (0.780)
Total 8 AD
CTR
0.13
0.12
0.87
0.88
103 (0.029)
103 (0.027)
708 (0.203)
721 (0.192)
2684 (0.768)
2923 (0.780)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs8192708

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1040566
rs1042521
rs1042523
rs1042531
rs1062601
rs1328756
rs1328757
rs1543375
rs17411904
rs1804160
rs2070756
rs2071023
rs2179706
rs6015032
rs6025639
rs6070157
rs8123020

AlzGene Recent Updates
AlzGene Top Results
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
Cure Alzheimer's Fund
Proud supporter of the AlzGene database.
Michael J. Fox Foundation
The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

NCRAD

The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.