AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs6859
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 Polymorphism: rs6859
 Gene: PVRL2  (HVEB; PRR2; CD112; PVRR2)  Entrez Gene    View on MSGene
 Protein: poliovirus receptor-related 2  (nectin 2; herpesvirus entry protein B)  ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 6 AD
CTR
0.52
0.42
0.48
0.58
1782 (0.273)
1898 (0.180)
3263 (0.500)
5105 (0.485)
1476 (0.226)
3521 (0.335)
Total 6 AD
CTR
0.52
0.42
0.48
0.58
1782 (0.273)
1898 (0.180)
3263 (0.500)
5105 (0.485)
1476 (0.226)
3521 (0.335)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs6859

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1001611
rs11549721
rs1531516
rs1871046
rs1985096
rs2075642
rs2306149
rs2436474
rs283809
rs283813
rs2927466
rs2927472
rs2972566
rs2972569
rs3112438
rs3112439
rs369599
rs370705
rs3729640
rs3745150
rs377702
rs3786502
rs3810143
rs3837923
rs384973
rs3852859
rs3852860
rs3852861
rs385982
rs3865427
rs387465
rs394221
rs395908
rs412776
rs416041
rs419010
rs419925
rs421812
rs440277
rs4452060
rs454050
rs4599021
rs4802240
rs4803765
rs4803766
rs4803767
rs510297
rs519113
rs519825
rs520283
rs521629
rs564724
rs6857
rs7254892
rs7507450
rs8104483
rs8112597

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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.