AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs1024611
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 Polymorphism: rs1024611 (-2518 G/A)
 Gene: CCL2  (MCP1; GDCF-2 HC11; MGC9434; HC11; MCAF; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30)  Entrez Gene    View on MSGene   View on PDGene   View on SZGene
 Protein: chemokine (C-C motif) ligand 2  (monocyte secretory protein JE; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; small inducible cytokine subfamily A (Cys-Cys), member 2; monocyte chemotactic protein 1, homologous to mouse Sig-je; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je))  ProteinLink
 Chromosome: 17   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 29 January 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 4 AD
CTR
0.25
0.24
0.75
0.76
74 (0.070)
43 (0.051)
388 (0.365)
316 (0.374)
602 (0.566)
485 (0.575)
 Asian 1 AD
CTR
0.62
0.64
0.38
0.36
70 (0.407)
136 (0.400)
73 (0.424)
166 (0.488)
29 (0.169)
38 (0.112)
Total 5 AD
CTR
0.30
0.36
0.70
0.65
144 (0.117)
179 (0.151)
461 (0.373)
482 (0.407)
631 (0.511)
523 (0.442)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1024611 (-2518 G/A)

Please also see disclaimer for more information on these meta-analyses.

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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.