AlzGene - Polymorphism Details
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 Study: Reitz, 2010
 Gene: KIF11  (KNSL1; TRIP5; EG5; HKSP)  Entrez Gene    View on PDGene
 Protein: kinesin family member 11   ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 12 September 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 13

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Hispanic
rs7078243 USA AD
CTR		 0.42
0.41		 0.58
0.59		 28 (0.177)
49 (0.167)		 77 (0.487)
142 (0.485)		 53 (0.335)
102 (0.348)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Hispanic
rs10882088 USA AD
CTR		 0.11
0.12		 0.89
0.88		 2 (0.013)
4 (0.014)		 31 (0.194)
62 (0.211)		 127 (0.794)
228 (0.776)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Hispanic
rs10882091 USA AD
CTR		 0.31
0.30		 0.69
0.70		 15 (0.094)
26 (0.089)		 68 (0.428)
123 (0.420)		 76 (0.478)
144 (0.491)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Hispanic
rs12256435 USA AD
CTR		 0.12
0.09		 0.88
0.91		 2 (0.013)
2 (0.007)		 34 (0.213)
48 (0.164)		 124 (0.775)
243 (0.829)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Hispanic
rs3824735 USA AD
CTR		 0.24
0.26		 0.76
0.74		 9 (0.057)
20 (0.068)		 58 (0.365)
113 (0.384)		 92 (0.579)
161 (0.548)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   min-Allele maj-Allele min/min
(frequency)		 min/maj
(frequency)		 maj/maj
(frequency)
 Hispanic
rs6583826 USA AD
CTR		 0.49
0.49		 0.51
0.51		 38 (0.238)
71 (0.241)		 80 (0.500)
147 (0.500)		 42 (0.263)
76 (0.259)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Hispanic
rs6583830 USA AD
CTR		 0.31
0.30		 0.69
0.70		 15 (0.094)
26 (0.089)		 68 (0.428)
123 (0.420)		 76 (0.478)
144 (0.491)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Hispanic
rs11187094 USA AD
CTR		 0.17
0.14		 0.83
0.86		 5 (0.031)
6 (0.020)		 45 (0.281)
71 (0.241)		 110 (0.688)
217 (0.738)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Hispanic
rs11818705 USA AD
CTR		 0.17
0.19		 0.83
0.81		 5 (0.031)
11 (0.037)		 45 (0.281)
90 (0.306)		 110 (0.688)
193 (0.656)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Hispanic
rs2275220 USA AD
CTR		 0.02
0.03		 0.98
0.97		 0 (0.000)
0 (0.000)		 6 (0.038)
17 (0.058)		 154 (0.963)
277 (0.942)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Hispanic
rs7914814 USA AD
CTR		 0.31
0.30		 0.69
0.70		 15 (0.094)
26 (0.089)		 68 (0.428)
123 (0.420)		 76 (0.478)
144 (0.491)


Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Hispanic
rs7070990 USA AD
CTR		 0.33
0.32		 0.67
0.68		 16 (0.106)
29 (0.102)		 67 (0.444)
123 (0.435)		 68 (0.450)
131 (0.463)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Hispanic
rs7917359 USA AD
CTR		 0.17
0.18		 0.83
0.82		 5 (0.031)
9 (0.031)		 45 (0.281)
86 (0.296)		 110 (0.688)
196 (0.674)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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