AlzGene - Polymorphism Details
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 Study: Cozza, 2008
 Gene: NTRK1  (MTC; TRK; TRK1; TRKA; p140-TrkA)  Entrez Gene
 Protein: neurotrophic tyrosine kinase, receptor, type 1   ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 May 2009
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 5

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6336 Italy AD
CTR
0.17
0.25
0.83
0.75
4 (0.016)
1 (0.010)
77 (0.307)
47 (0.485)
170 (0.677)
49 (0.505)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs6339 Italy AD
CTR
0.06
0.09
0.94
0.91
0 (0.000)
0 (0.000)
31 (0.124)
17 (0.175)
220 (0.876)
80 (0.825)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   del-Allele ins-Allele del/del
(frequency)
del/ins
(frequency)
ins/ins
(frequency)
 Caucasian
rs1799770 Italy AD
CTR
0.06
0.05
0.94
0.95
1 (0.004)
0 (0.000)
27 (0.108)
10 (0.103)
223 (0.888)
87 (0.897)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs3753213 Italy AD
CTR
0.18
0.13
0.82
0.87
11 (0.044)
1 (0.010)
67 (0.267)
24 (0.247)
173 (0.689)
72 (0.742)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs1800878 Italy AD
CTR
0.02
0.05
0.98
0.95
3 (0.012)
3 (0.031)
6 (0.024)
3 (0.031)
242 (0.964)
91 (0.938)
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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