AlzGene - Polymorphism Details
Back Search Methods Disclaimer Credits
 Study: Lee, 2008
 Gene: NCAPD2  (CAP-D2; CNAP1; KIAA0159; hCAP-D2)  Entrez Gene
 Protein: non-SMC condensin I complex, subunit D2  (chromosome condensation related SMC associated protein 1; chromosome condensation-related SMC-associated protein 1)  ProteinLink
 Chromosome: 12   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 4

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2072373 Mixed (Northern European) AD
CTR
0.12
0.14
0.88
0.86
3 (0.016)
4 (0.018)
39 (0.212)
54 (0.241)
142 (0.772)
166 (0.741)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs7311174 Mixed (Northern European) AD
CTR
0.29
0.28
0.71
0.72
15 (0.082)
18 (0.080)
75 (0.412)
90 (0.402)
92 (0.505)
116 (0.518)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2072374 Mixed (Northern European) AD
CTR
0.29
0.28
0.71
0.72
15 (0.082)
18 (0.080)
75 (0.412)
90 (0.402)
92 (0.505)
116 (0.518)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs740850 Mixed (Northern European) AD
CTR
0.40
0.33
0.60
0.67
29 (0.158)
24 (0.107)
88 (0.481)
99 (0.442)
66 (0.361)
101 (0.451)


Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2072373 Mixed (Northern European) AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
 Hispanic
rs2072373 USA, Caribbean AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs7311174 Mixed (Northern European) AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
 Hispanic
rs7311174 USA, Caribbean AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2072374 Mixed (Northern European) AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
 Hispanic
rs2072374 USA, Caribbean AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs740850 Mixed (Northern European) AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
 Hispanic
rs740850 USA, Caribbean AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
AlzGene Recent Updates
AlzGene Top Results
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
Cure Alzheimer's Fund
Proud supporter of the AlzGene database.
Michael J. Fox Foundation
The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

NCRAD

The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.