AlzGene - Polymorphism Details
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 Study: Minster, 2008
 Gene: SORL1  (GP250; LR11; LRP9; SorLA; SorLA-1)  Entrez Gene
 Protein: Sortilin-related receptor  (Sorting protein-related receptor containing LDLR class A repeats; SorLA; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 6

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele T-Allele G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian
rs2070045 USA AD
CTR
0.22
0.22
0.78
0.78
49 (0.049)
57 (0.057)
342 (0.344)
335 (0.335)
603 (0.607)
609 (0.608)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs3824968 USA AD
CTR
0.31
0.32
0.69
0.68
84 (0.079)
95 (0.087)
480 (0.452)
511 (0.467)
498 (0.469)
488 (0.446)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs641120 USA AD
CTR
0.41
0.42
0.59
0.58
173 (0.172)
169 (0.169)
482 (0.480)
506 (0.507)
349 (0.348)
324 (0.324)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs661057 USA AD
CTR
0.42
0.42
0.58
0.58
174 (0.174)
171 (0.171)
490 (0.490)
491 (0.491)
336 (0.336)
339 (0.339)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs668387 USA AD
CTR
0.41
0.42
0.59
0.58
175 (0.174)
164 (0.163)
475 (0.473)
516 (0.514)
355 (0.353)
324 (0.323)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs689021 USA AD
CTR
0.42
0.42
0.58
0.58
178 (0.178)
168 (0.167)
477 (0.477)
510 (0.508)
345 (0.345)
326 (0.325)
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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