AlzGene - Polymorphism Details
Back Search Methods Disclaimer Credits
 Study: Shibata, 2008
 Gene: SORL1  (GP250; LR11; LRP9; SorLA; SorLA-1)  Entrez Gene
 Protein: Sortilin-related receptor  (Sorting protein-related receptor containing LDLR class A repeats; SorLA; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LR11)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 7

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Asian
rs1010159 Japan AD
CTR
0.45
0.44
0.55
0.56
32 (0.187)
23 (0.177)
91 (0.532)
68 (0.523)
48 (0.281)
39 (0.300)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Asian
rs1699102 Japan AD
CTR
0.74
0.79
0.26
0.21
101 (0.561)
80 (0.615)
64 (0.356)
45 (0.346)
15 (0.083)
5 (0.038)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Asian
rs2282649 Japan AD
CTR
0.51
0.43
0.49
0.57
43 (0.257)
22 (0.169)
85 (0.509)
68 (0.523)
39 (0.234)
40 (0.308)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Asian
rs3824968 Japan AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Asian
rs641120 Japan AD
CTR
0.46
0.41
0.54
0.59
36 (0.200)
16 (0.124)
95 (0.528)
74 (0.574)
49 (0.272)
39 (0.302)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Asian
rs668387 Japan AD
CTR
0.49
0.57
0.51
0.43
40 (0.222)
44 (0.338)
98 (0.544)
61 (0.469)
42 (0.233)
25 (0.192)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Asian
rs689021 Japan AD
CTR
0.45
0.40
0.55
0.60
37 (0.206)
20 (0.154)
87 (0.483)
65 (0.500)
56 (0.311)
45 (0.346)
AlzGene Recent Updates
AlzGene Top Results
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
Cure Alzheimer's Fund
Proud supporter of the AlzGene database.
Michael J. Fox Foundation
The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

NCRAD

The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.