AlzGene - Polymorphism Details
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 Study: Yu, 2007
 Gene: TOMM40  (TOM40; PEREC1; C19orf1; PER-EC1; D19S1177E)  Entrez Gene    View on MSGene
 Protein: translocase of outer mitochondrial membrane 40 homolog (yeast)   ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 8

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs157581 USA AD
CTR		 0.41
0.21		 0.59
0.79		 33 (0.171)
10 (0.043)		 94 (0.487)
77 (0.332)		 66 (0.342)
145 (0.625)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs157580 USA AD
CTR		 0.29
0.41		 0.71
0.59		 16 (0.082)
39 (0.169)		 79 (0.407)
112 (0.485)		 99 (0.510)
80 (0.346)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Caucasian
TOMM40_novel USA AD
CTR		 0.38
0.18		 0.62
0.82		 28 (0.145)
8 (0.034)		 91 (0.472)
69 (0.297)		 74 (0.383)
155 (0.668)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs10119 USA AD
CTR		 0.45
0.32		 0.55
0.68		 39 (0.202)
24 (0.103)		 96 (0.497)
101 (0.435)		 58 (0.301)
107 (0.461)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs11556505 USA AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs157584 USA AD
CTR		 0.42
0.44		 0.58
0.56		 34 (0.176)
44 (0.190)		 94 (0.487)
114 (0.491)		 65 (0.337)
74 (0.319)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs157590 USA AD
CTR		 0.40
0.45		 0.60
0.55		 31 (0.160)
47 (0.203)		 93 (0.479)
115 (0.496)		 70 (0.361)
70 (0.302)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs741780 USA AD
CTR		 0.32
0.39		 0.68
0.61		 20 (0.104)
36 (0.155)		 85 (0.440)
111 (0.478)		 88 (0.456)
85 (0.366)
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