AlzGene - Polymorphism Details
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 Study: Wollmer, 2007
 Gene: ABCG1  (ABC8; WHITE1)  Entrez Gene
 Protein: ATP-binding cassette, sub-family G (WHITE), member 1  (ABC transporter 8; white protein homolog (drosophila))  ProteinLink
 Chromosome: 21   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 8

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   min-Allele maj-Allele min/min
(frequency)
min/maj
(frequency)
maj/maj
(frequency)
 Caucasian
rs1044317 Switzerland AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele A-Allele C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian
rs1378577 Switzerland AD
CTR
0.30
0.22
0.70
0.78
10 (0.072)
6 (0.030)
64 (0.464)
78 (0.386)
64 (0.464)
118 (0.584)
rs1378577 Belgium AD
CTR
0.23
0.20
0.77
0.80
34 (0.047)
24 (0.052)
258 (0.357)
138 (0.299)
431 (0.596)
300 (0.649)
rs1378577 Germany AD
CTR
0.28
0.21
0.73
0.79
2 (0.050)
2 (0.027)
18 (0.450)
28 (0.373)
20 (0.500)
45 (0.600)
rs1378577 Greece AD
CTR
0.24
0.26
0.76
0.74
18 (0.068)
8 (0.082)
91 (0.343)
34 (0.351)
156 (0.589)
55 (0.567)
rs1378577 Poland AD
CTR
0.24
0.30
0.76
0.70
11 (0.051)
16 (0.068)
84 (0.387)
110 (0.464)
122 (0.562)
111 (0.468)
rs1378577 Sweden AD
CTR
0.27
0.25
0.73
0.75
16 (0.086)
9 (0.055)
69 (0.369)
64 (0.388)
102 (0.545)
92 (0.558)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   min-Allele maj-Allele min/min
(frequency)
min/maj
(frequency)
maj/maj
(frequency)
 Caucasian
rs225378 Switzerland AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs225448 Switzerland AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs3827225 Switzerland AD
CTR
0.22
0.29
0.78
0.71
2 (0.014)
14 (0.070)
59 (0.413)
89 (0.443)
82 (0.573)
98 (0.488)
rs3827225 Poland AD
CTR
0.22
0.23
0.78
0.77
14 (0.064)
15 (0.064)
69 (0.317)
77 (0.328)
135 (0.619)
143 (0.609)
rs3827225 Greece AD
CTR
0.26
0.24
0.74
0.76
16 (0.059)
4 (0.041)
106 (0.394)
40 (0.408)
147 (0.546)
54 (0.551)
rs3827225 Germany AD
CTR
0.35
0.28
0.65
0.72
7 (0.175)
5 (0.068)
14 (0.350)
31 (0.419)
19 (0.475)
38 (0.514)
rs3827225 Belgium AD
CTR
0.26
0.24
0.74
0.76
56 (0.079)
26 (0.059)
252 (0.353)
159 (0.358)
405 (0.568)
259 (0.583)
rs3827225 Sweden AD
CTR
0.24
0.23
0.76
0.77
14 (0.074)
6 (0.037)
64 (0.337)
63 (0.384)
112 (0.589)
95 (0.579)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   min-Allele maj-Allele min/min
(frequency)
min/maj
(frequency)
maj/maj
(frequency)
 Caucasian
rs425215 Switzerland AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs692383 Switzerland AD
CTR
0.39
0.28
0.61
0.72
21 (0.151)
14 (0.073)
67 (0.482)
80 (0.415)
51 (0.367)
99 (0.513)
rs692383 Belgium AD
CTR
0.31
0.31
0.69
0.69
71 (0.100)
44 (0.098)
303 (0.428)
188 (0.418)
334 (0.472)
218 (0.484)
rs692383 Germany AD
CTR
0.36
0.33
0.64
0.67
3 (0.077)
10 (0.145)
22 (0.564)
26 (0.377)
14 (0.359)
33 (0.478)
rs692383 Greece AD
CTR
0.36
0.36
0.64
0.64
36 (0.134)
11 (0.115)
119 (0.442)
47 (0.490)
114 (0.424)
38 (0.396)
rs692383 Poland AD
CTR
0.34
0.39
0.66
0.61
23 (0.106)
32 (0.138)
102 (0.468)
115 (0.496)
93 (0.427)
85 (0.366)
rs692383 Sweden AD
CTR
0.34
0.31
0.66
0.69
23 (0.126)
16 (0.102)
78 (0.426)
66 (0.420)
82 (0.448)
75 (0.478)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   min-Allele maj-Allele min/min
(frequency)
min/maj
(frequency)
maj/maj
(frequency)
 Caucasian
rs9976212 Switzerland AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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