AlzGene - Polymorphism Details
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 Study: Wollmer, 2007
 Gene: ACAD8  (ACAD-8)  Entrez Gene
 Protein: acyl-Coenzyme A dehydrogenase family, member 8  (acyl-coenzyme A dehydrogenase 8)  ProteinLink
 Chromosome: 11   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 29 January 2010
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs514417 Belgium AD
CTR
0.32
0.34
0.68
0.66
75 (0.104)
48 (0.104)
309 (0.430)
214 (0.464)
335 (0.466)
199 (0.432)
rs514417 Germany AD
CTR
0.39
0.36
0.61
0.64
6 (0.158)
8 (0.118)
18 (0.474)
33 (0.485)
14 (0.368)
27 (0.397)
rs514417 Greece AD
CTR
0.33
0.34
0.67
0.66
24 (0.090)
11 (0.112)
129 (0.485)
44 (0.449)
113 (0.425)
43 (0.439)
rs514417 Poland AD
CTR
0.31
0.32
0.69
0.68
16 (0.079)
21 (0.090)
94 (0.463)
109 (0.468)
93 (0.458)
103 (0.442)
rs514417 Sweden AD
CTR
0.26
0.22
0.74
0.78
11 (0.061)
9 (0.057)
70 (0.389)
50 (0.318)
99 (0.550)
98 (0.624)
rs514417 Switzerland AD
CTR
0.35
0.30
0.65
0.70
23 (0.162)
16 (0.079)
53 (0.373)
88 (0.436)
66 (0.465)
98 (0.485)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs561945 Belgium AD
CTR
0.32
0.33
0.68
0.67
75 (0.105)
48 (0.106)
304 (0.426)
207 (0.456)
334 (0.468)
199 (0.438)
rs561945 Germany AD
CTR
0.37
0.36
0.63
0.64
6 (0.154)
8 (0.108)
17 (0.436)
37 (0.500)
16 (0.410)
29 (0.392)
rs561945 Greece AD
CTR
0.34
0.34
0.66
0.66
27 (0.100)
11 (0.113)
129 (0.480)
44 (0.454)
113 (0.420)
42 (0.433)
rs561945 Poland AD
CTR
0.32
0.32
0.68
0.68
18 (0.083)
20 (0.085)
105 (0.482)
112 (0.477)
95 (0.436)
103 (0.438)
rs561945 Sweden AD
CTR
0.26
0.22
0.74
0.78
12 (0.067)
9 (0.058)
70 (0.393)
52 (0.333)
96 (0.539)
95 (0.609)
rs561945 Switzerland AD
CTR
0.35
0.30
0.65
0.70
22 (0.155)
17 (0.083)
54 (0.380)
87 (0.426)
66 (0.465)
100 (0.490)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs570113 Belgium AD
CTR
0.34
0.35
0.66
0.65
87 (0.120)
54 (0.117)
320 (0.442)
212 (0.460)
317 (0.438)
195 (0.423)
rs570113 Germany AD
CTR
0.38
0.38
0.62
0.62
6 (0.154)
8 (0.110)
18 (0.462)
40 (0.548)
15 (0.385)
25 (0.342)
rs570113 Greece AD
CTR
0.35
0.34
0.65
0.66
28 (0.105)
11 (0.115)
129 (0.483)
44 (0.458)
110 (0.412)
41 (0.427)
rs570113 Poland AD
CTR
0.34
0.33
0.66
0.67
22 (0.100)
20 (0.085)
105 (0.477)
113 (0.481)
93 (0.423)
102 (0.434)
rs570113 Sweden AD
CTR
0.27
0.23
0.73
0.77
11 (0.058)
10 (0.063)
80 (0.423)
55 (0.344)
98 (0.519)
95 (0.594)
rs570113 Switzerland AD
CTR
0.35
0.30
0.65
0.70
23 (0.162)
16 (0.079)
52 (0.366)
91 (0.448)
67 (0.472)
96 (0.473)
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Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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