AlzGene

AlzGene - Polymorphism Details

Study:

Seripa, 2008

Gene:

RELN (RL; PRO1598)

View on SZGene

Protein:

reelin

Chromosome:

7 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 5 July 2008

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs2229864	Italy	AD CTR	0.39 0.37	0.61 0.63	13 (0.176) 13 (0.140)	32 (0.432) 43 (0.462)	29 (0.392) 37 (0.398)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs607755	Italy	AD CTR	0.45 0.48	0.55 0.52	16 (0.216) 23 (0.247)	34 (0.459) 43 (0.462)	24 (0.324) 27 (0.290)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		8-Allele	10-Allele	8/8 (frequency)	8/10 (frequency)	10/10 (frequency)
Caucasian
RELN_VNTR	Italy	AD CTR	0.43 0.48	0.57 0.52	14 (0.189) 19 (0.204)	36 (0.486) 51 (0.548)	24 (0.324) 23 (0.247)

AlzGene Recent Updates

AlzGene Top Results

Top Results Details

1.	APOE_e2/3/4
2.	BIN1
3.	CLU
4.	ABCA7
5.	CR1
6.	PICALM
7.	MS4A6A
8.	CD33
9.	MS4A4E
10.	CD2AP

AlzGene Stats

Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320

Proud supporter of the AlzGene database.

The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

NCRAD

The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.

ALSGene

AlzGene

MSGene

PDGene

SZGene

An up-to-date collection of all published genetic association studies.