AlzGene - Polymorphism Details
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 Study: Zou, 2010
 Gene: IDE  (INSULYSIN)  Entrez Gene    View on PDGene
 Protein: insulin-degrading enzyme  (insulysin; insulinase)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 12

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs2149632 (IDE_12) Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs2149632 (IDE_12) Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs2149632 (IDE_12) Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs11187060 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187060 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187060 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs11187064 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187064 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187064 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs1999763 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs1999763 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs1999763 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs11187025 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187025 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs11187025 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs3737225 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs3737225 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs3737225 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele A-Allele C/C
(frequency)		 C/A
(frequency)		 A/A
(frequency)
 Caucasian
rs7078413 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7078413 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7078413 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs7908111 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7908111 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7908111 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs10786044 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs10786044 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs10786044 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2901587 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs2901587 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs2901587 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7086285 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7086285 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
rs7086285 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs7910977 Overlaps with Carrasquillo, 2010 (USA-AUT) AD
CTR		 0.09
0.12		 0.91
0.88		 8 (0.015)
6 (0.019)		 76 (0.146)
64 (0.198)		 437 (0.839)
254 (0.784)
rs7910977 Overlaps with Carrasquillo, 2010 (USA-JS) AD
CTR		 0.11
0.14		 0.89
0.86		 8 (0.014)
10 (0.017)		 105 (0.184)
139 (0.243)		 459 (0.802)
424 (0.740)
rs7910977 Overlaps with Carrasquillo, 2010 (USA-NCRAD) AD
CTR		 0.12
0.12		 0.88
0.88		 17 (0.025)
3 (0.015)		 127 (0.185)
44 (0.217)		 543 (0.790)
156 (0.768)
rs7910977 Overlaps with Carrasquillo, 2010 (USA-RS) AD
CTR		 0.13
0.14		 0.87
0.86		 10 (0.020)
18 (0.014)		 112 (0.224)
325 (0.251)		 378 (0.756)
953 (0.735)
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Genes: 695
Polymorphisms: 2973
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