AlzGene

AlzGene - Polymorphism Details

Study:

Chapuis, 2009

Gene:

IL33 (DVS27; C9orf26; NFEHEV; NF-HEV)

Protein:

interleukin 33

Chromosome:

9 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 29 January 2010

Total number of polymorphisms investigated by this study: 12

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	C-Allele	G/G (frequency)	G/C (frequency)	C/C (frequency)
Caucasian
rs1157505	France	AD CTR	0.19 0.23	0.81 0.77	26 (0.034) 42 (0.063)	238 (0.308) 224 (0.333)	508 (0.658) 406 (0.604)
rs1157505	UK	AD CTR	0.26 0.25	0.74 0.75	25 (0.068) 12 (0.061)	143 (0.386) 75 (0.379)	202 (0.546) 111 (0.561)
rs1157505	USA	AD CTR	0.23 0.23	0.77 0.77	43 (0.059) 37 (0.051)	246 (0.338) 267 (0.366)	439 (0.603) 426 (0.584)
rs1157505	France (3C)	AD CTR	0.15 0.20	0.85 0.80	4 (0.018) 273 (0.044)	59 (0.261) 1994 (0.322)	163 (0.721) 3932 (0.634)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs11792633	France (3C)	AD CTR	0.22 0.30	0.78 0.70	13 (0.058) 550 (0.089)	74 (0.327) 2602 (0.420)	139 (0.615) 3047 (0.492)
rs11792633	France	AD CTR	0.28 0.32	0.72 0.68	52 (0.070) 61 (0.094)	307 (0.414) 287 (0.443)	383 (0.516) 300 (0.463)
rs11792633	UK	AD CTR	0.30 0.32	0.70 0.68	27 (0.073) 17 (0.086)	165 (0.446) 94 (0.475)	178 (0.481) 87 (0.439)
rs11792633	USA	AD CTR	0.32 0.32	0.68 0.68	72 (0.099) 73 (0.100)	317 (0.435) 320 (0.438)	339 (0.466) 337 (0.462)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs7044343	France	AD CTR	0.33 0.38	0.67 0.62	76 (0.100) 90 (0.138)	356 (0.467) 320 (0.492)	331 (0.434) 241 (0.370)
rs7044343	UK	AD CTR	0.35 0.39	0.65 0.61	42 (0.114) 26 (0.131)	178 (0.481) 102 (0.515)	150 (0.405) 70 (0.354)
rs7044343	USA	AD CTR	0.38 0.38	0.62 0.62	103 (0.141) 105 (0.144)	352 (0.484) 351 (0.481)	273 (0.375) 274 (0.375)
rs7044343	France (3C)	AD CTR	0.29 0.36	0.71 0.64	23 (0.102) 799 (0.129)	85 (0.376) 2850 (0.460)	118 (0.522) 2550 (0.411)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs10975511	France	AD CTR	0.28 0.29	0.72 0.71	24 (0.082) 20 (0.088)	115 (0.394) 93 (0.410)	153 (0.524) 114 (0.502)
rs10975511	USA	AD CTR	0.26 0.31	0.74 0.69	16 (0.081) 18 (0.092)	70 (0.354) 85 (0.434)	112 (0.566) 93 (0.474)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs16924144	France	AD CTR	0.31 0.35	0.69 0.65	27 (0.097) 30 (0.135)	118 (0.424) 98 (0.439)	133 (0.478) 95 (0.426)
rs16924144	USA	AD CTR	0.34 0.37	0.66 0.63	22 (0.113) 28 (0.146)	89 (0.459) 86 (0.448)	83 (0.428) 78 (0.406)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs16924159	France	AD CTR	0.29 0.31	0.71 0.69	25 (0.092) 21 (0.098)	107 (0.395) 92 (0.430)	139 (0.513) 101 (0.472)
rs16924159	USA	AD CTR	0.33 0.37	0.67 0.63	22 (0.112) 27 (0.137)	86 (0.437) 93 (0.472)	89 (0.452) 77 (0.391)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs16924161	France	AD CTR	0.12 0.14	0.88 0.86	5 (0.018) 4 (0.018)	57 (0.204) 55 (0.249)	218 (0.779) 162 (0.733)
rs16924161	USA	AD CTR	0.14 0.16	0.86 0.84	3 (0.015) 6 (0.030)	49 (0.246) 51 (0.256)	147 (0.739) 142 (0.714)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	A-Allele	C/C (frequency)	C/A (frequency)	A/A (frequency)
Caucasian
rs1891385	France	AD CTR	0.12 0.13	0.88 0.88	6 (0.021) 2 (0.010)	56 (0.199) 48 (0.231)	220 (0.780) 158 (0.760)
rs1891385	USA	AD CTR	0.14 0.09	0.86 0.91	6 (0.030) 3 (0.016)	43 (0.217) 30 (0.158)	149 (0.753) 157 (0.826)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs7035413	France	AD CTR	0.28 0.22	0.72 0.78	23 (0.080) 7 (0.030)	114 (0.399) 89 (0.385)	149 (0.521) 135 (0.584)
rs7035413	USA	AD CTR	0.22 0.19	0.78 0.81	7 (0.035) 10 (0.051)	74 (0.370) 55 (0.278)	119 (0.595) 133 (0.672)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs7848215	France	AD CTR	0.31 0.25	0.69 0.75	27 (0.098) 12 (0.055)	119 (0.433) 86 (0.396)	129 (0.469) 119 (0.548)
rs7848215	USA	AD CTR	0.29 0.24	0.71 0.76	16 (0.082) 12 (0.061)	82 (0.418) 70 (0.357)	98 (0.500) 114 (0.582)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs8172	France	AD CTR	0.08 0.09	0.92 0.91	0 (0.000) 1 (0.003)	38 (0.163) 49 (0.169)	195 (0.837) 240 (0.828)
rs8172	USA	AD CTR	0.06 0.10	0.94 0.90	1 (0.005) 2 (0.010)	23 (0.119) 33 (0.170)	170 (0.876) 159 (0.820)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	C-Allele	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian
rs996029	France	AD CTR	0.04 0.05	0.96 0.95	0 (0.000) 0 (0.000)	23 (0.082) 20 (0.094)	259 (0.918) 192 (0.906)
rs996029	USA	AD CTR	0.04 0.04	0.96 0.96	0 (0.000) 0 (0.000)	15 (0.076) 16 (0.082)	182 (0.924) 180 (0.918)

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