AlzGene - Polymorphism Details
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 Study: Szymanski, 2008
 Gene: NUMB  (S171; NUMB)  Entrez Gene
 Protein: numb homolog (Drosophila)   ProteinLink
 Chromosome: 14   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 8

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs10141031 USA AD
CTR		 0.19
0.20		 0.81
0.80		 11 (0.052)
6 (0.043)		 57 (0.270)
44 (0.319)		 143 (0.678)
88 (0.638)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs1047849 USA AD
CTR		 0.19
0.19		 0.81
0.81		 6 (0.027)
4 (0.027)		 72 (0.329)
48 (0.322)		 141 (0.644)
97 (0.651)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs177378 USA AD
CTR		 0.24
0.23		 0.76
0.77		 8 (0.038)
7 (0.051)		 87 (0.408)
50 (0.365)		 118 (0.554)
80 (0.584)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele G-Allele C/C
(frequency)		 C/G
(frequency)		 G/G
(frequency)
 Caucasian
rs177380 USA AD
CTR		 0.30
0.24		 0.70
0.76		 17 (0.077)
7 (0.047)		 99 (0.448)
58 (0.389)		 105 (0.475)
84 (0.564)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2108552 USA AD
CTR		 0.14
0.17		 0.86
0.83		 7 (0.032)
4 (0.027)		 47 (0.213)
42 (0.282)		 167 (0.756)
103 (0.691)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2293797 USA AD
CTR		 0.09
0.11		 0.91
0.89		 1 (0.005)
2 (0.013)		 38 (0.173)
29 (0.193)		 181 (0.823)
119 (0.793)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs4899468 USA AD
CTR		 0.29
0.26		 0.71
0.74		 15 (0.068)
12 (0.079)		 98 (0.441)
55 (0.364)		 109 (0.491)
84 (0.556)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs6574115 USA AD
CTR		 0.46
0.48		 0.54
0.52		 50 (0.228)
36 (0.245)		 103 (0.470)
70 (0.476)		 66 (0.301)
41 (0.279)
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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