AlzGene - Polymorphism Details
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 Study: Szymanski, 2008
 Gene: TMEM63C  (C14orf171)  Entrez Gene
 Protein: transmembrane protein 63C   ProteinLink
 Chromosome: 14   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 10

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs11847091 USA (NIMH, NCRAD) AD
CTR
0.27
0.30
0.73
0.70
29 (0.083)
21 (0.073)
130 (0.372)
129 (0.451)
190 (0.544)
136 (0.476)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs369202 USA (NIMH, NCRAD) AD
CTR
0.19
0.23
0.81
0.77
12 (0.034)
15 (0.052)
109 (0.311)
105 (0.363)
230 (0.655)
169 (0.585)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs3813539 USA (NIMH, NCRAD) AD
CTR
0.13
0.15
0.87
0.85
5 (0.014)
6 (0.021)
80 (0.229)
72 (0.249)
265 (0.757)
211 (0.730)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs7141596 USA (NIMH, NCRAD) AD
CTR
0.02
0.00
0.98
1.00
0 (0.000)
0 (0.000)
11 (0.031)
2 (0.007)
340 (0.969)
286 (0.993)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs733416 USA (NIMH, NCRAD) AD
CTR
0.23
0.16
0.77
0.84
26 (0.074)
7 (0.024)
109 (0.311)
77 (0.267)
215 (0.614)
204 (0.708)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs747273 USA (NIMH, NCRAD) AD
CTR
0.45
0.44
0.55
0.56
73 (0.215)
55 (0.196)
157 (0.462)
140 (0.498)
110 (0.324)
86 (0.306)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs8021076 USA (NIMH, NCRAD) AD
CTR
0.11
0.10
0.89
0.90
5 (0.014)
1 (0.003)
65 (0.185)
57 (0.197)
281 (0.801)
231 (0.799)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs888059 USA (NIMH, NCRAD) AD
CTR
0.31
0.24
0.69
0.76
42 (0.120)
15 (0.052)
132 (0.376)
110 (0.381)
177 (0.504)
164 (0.567)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs888060 USA (NIMH, NCRAD) AD
CTR
0.15
0.17
0.85
0.83
10 (0.029)
3 (0.011)
85 (0.249)
88 (0.313)
246 (0.721)
190 (0.676)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs368855 USA (NIMH, NCRAD) AD
CTR
0.24
0.20
0.76
0.80
26 (0.074)
8 (0.028)
117 (0.334)
97 (0.336)
207 (0.591)
184 (0.637)
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Genes: 695
Polymorphisms: 2973
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