AlzGene

AlzGene - Polymorphism Details

Study:

Pinho, 2009

Gene:

PITRM1 (RP11-298E9.1; KIAA1104; MGC138192; MGC141929; MP1; PreP; hMP1)

Protein:

pitrilysin metallopeptidase 1 (PreP peptidasome; metalloprotease 1; metalloprotease 1 (pitrilysin family); pitrilysin metalloproteinase 1)

Chromosome:

10 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 18 April 2011

Total number of polymorphisms investigated by this study: 17

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs2306319	Sweden	AD CTR	0.27 0.28	0.73 0.72	51 (0.078) 46 (0.072)	245 (0.375) 265 (0.412)	357 (0.547) 332 (0.516)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs2388560	Sweden	AD CTR	0.37 0.39	0.63 0.61	94 (0.143) 103 (0.159)	293 (0.445) 297 (0.458)	271 (0.412) 248 (0.383)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs3182535	Sweden	AD CTR	0.30 0.29	0.70 0.71	53 (0.081) 47 (0.073)	280 (0.429) 280 (0.433)	320 (0.490) 320 (0.495)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs3740607	Sweden	AD CTR	0.49 0.48	0.51 0.52	153 (0.236) 145 (0.224)	327 (0.505) 329 (0.509)	167 (0.258) 172 (0.266)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs3752802	Sweden	AD CTR	0.24 0.26	0.76 0.74	44 (0.068) 36 (0.056)	226 (0.349) 264 (0.410)	378 (0.583) 344 (0.534)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	C-Allele	G/G (frequency)	G/C (frequency)	C/C (frequency)
Caucasian
rs3765101	Sweden	AD CTR	0.08 0.08	0.92 0.92	0 (0.000) 0 (0.000)	104 (0.161) 100 (0.155)	540 (0.839) 546 (0.845)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs3814596	Sweden	AD CTR	0.20 0.21	0.80 0.79	29 (0.044) 26 (0.040)	202 (0.306) 220 (0.341)	430 (0.651) 400 (0.619)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs4242746	Sweden	AD CTR	0.33 0.30	0.67 0.70	63 (0.099) 59 (0.091)	300 (0.470) 273 (0.422)	275 (0.431) 315 (0.487)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	C-Allele	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian
rs4242748	Sweden	AD CTR	0.30 0.27	0.70 0.73	56 (0.086) 47 (0.075)	276 (0.425) 247 (0.395)	317 (0.488) 332 (0.530)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs4609511	Sweden	AD CTR	0.29 0.27	0.71 0.73	55 (0.085) 47 (0.073)	269 (0.414) 257 (0.398)	326 (0.502) 341 (0.529)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs4880597	Sweden	AD CTR	0.48 0.49	0.52 0.51	144 (0.221) 144 (0.223)	340 (0.521) 338 (0.524)	168 (0.258) 163 (0.253)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs4881109	Sweden	AD CTR	0.27 0.25	0.73 0.75	45 (0.069) 40 (0.062)	258 (0.393) 247 (0.382)	353 (0.538) 360 (0.556)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	A-Allele	C/C (frequency)	C/A (frequency)	A/A (frequency)
Caucasian
rs6602033	Sweden	AD CTR	0.30 0.27	0.70 0.73	54 (0.083) 46 (0.072)	278 (0.428) 259 (0.405)	318 (0.489) 335 (0.523)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	T-Allele	C/C (frequency)	C/T (frequency)	T/T (frequency)
Caucasian
rs7079217	Sweden	AD CTR	0.15 0.16	0.85 0.84	14 (0.021) 10 (0.015)	168 (0.255) 189 (0.292)	476 (0.723) 448 (0.692)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs7898695	Sweden	AD CTR	0.41 0.40	0.59 0.60	107 (0.165) 102 (0.159)	317 (0.488) 309 (0.481)	225 (0.347) 231 (0.360)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs7900718	Sweden	AD CTR	0.32 0.30	0.68 0.70	64 (0.098) 59 (0.091)	292 (0.446) 270 (0.417)	299 (0.456) 319 (0.492)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	G-Allele	C/C (frequency)	C/G (frequency)	G/G (frequency)
Caucasian
rs9423705	Sweden	AD CTR	0.32 0.32	0.68 0.68	69 (0.106) 66 (0.102)	280 (0.428) 285 (0.440)	305 (0.466) 297 (0.458)

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