AlzGene - Polymorphism Details
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 Study: Giedraitis, 2009
 Gene: IGF1  (IGF1A; IGFI)  Entrez Gene    View on SZGene
 Protein: insulin-like growth factor 1 (somatomedin C)  (OTTHUMP00000195084; insulin-like growth factor 1)  ProteinLink
 Chromosome: 12   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 17

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele A-Allele T/T
(frequency)		 T/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2288377 Sweden (ULSAM) AD
CTR		 0.05
0.03		 0.95
0.97		 0 (0.000)
0 (0.000)		 8 (0.096)
20 (0.052)		 75 (0.904)
363 (0.948)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6219 Sweden (ULSAM) AD
CTR		 0.09
0.10		 0.91
0.90		 1 (0.012)
2 (0.005)		 13 (0.155)
68 (0.183)		 70 (0.833)
301 (0.811)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs2195240 Sweden (ULSAM) AD
CTR		 0.24
0.26		 0.76
0.74		 4 (0.048)
24 (0.063)		 32 (0.381)
149 (0.392)		 48 (0.571)
207 (0.545)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs2288378 Sweden (ULSAM) AD
CTR		 0.25
0.23		 0.75
0.77		 5 (0.060)
20 (0.052)		 32 (0.381)
138 (0.361)		 47 (0.560)
224 (0.586)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs10735380 Sweden (ULSAM) AD
CTR		 0.26
0.27		 0.74
0.73		 5 (0.060)
26 (0.068)		 34 (0.405)
156 (0.408)		 45 (0.536)
200 (0.524)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Caucasian
rs6220 Sweden (ULSAM) AD
CTR		 0.30
0.28		 0.70
0.72		 6 (0.082)
26 (0.076)		 32 (0.438)
138 (0.404)		 35 (0.479)
178 (0.520)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs978458 Sweden (ULSAM) AD
CTR		 0.28
0.25		 0.72
0.75		 7 (0.089)
23 (0.061)		 30 (0.380)
141 (0.371)		 42 (0.532)
216 (0.568)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs6214 Sweden (ULSAM) AD
CTR		 0.46
0.41		 0.54
0.59		 22 (0.262)
65 (0.171)		 34 (0.405)
185 (0.486)		 28 (0.333)
131 (0.344)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs7136446 Sweden (ULSAM) AD
CTR		 0.37
0.37		 0.63
0.63		 10 (0.122)
53 (0.141)		 41 (0.500)
169 (0.451)		 31 (0.378)
153 (0.408)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs5742667 Sweden (ULSAM) AD
CTR		 0.29
0.25		 0.71
0.75		 8 (0.099)
23 (0.061)		 31 (0.383)
143 (0.378)		 42 (0.519)
212 (0.561)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs9989002 Sweden (ULSAM) AD
CTR		 0.27
0.27		 0.73
0.73		 5 (0.063)
26 (0.070)		 33 (0.413)
149 (0.399)		 42 (0.525)
198 (0.531)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele G-Allele C/C
(frequency)		 C/G
(frequency)		 G/G
(frequency)
 Caucasian
rs5742678 Sweden (ULSAM) AD
CTR		 0.29
0.25		 0.71
0.75		 8 (0.095)
23 (0.061)		 33 (0.393)
144 (0.381)		 43 (0.512)
211 (0.558)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs35767 Sweden (ULSAM) AD
CTR		 0.21
0.13		 0.79
0.87		 3 (0.036)
6 (0.016)		 29 (0.345)
86 (0.227)		 52 (0.619)
287 (0.757)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs35766 Sweden (ULSAM) AD
CTR		 0.19
0.13		 0.81
0.87		 2 (0.024)
6 (0.016)		 28 (0.337)
87 (0.229)		 53 (0.639)
287 (0.755)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs5742671 Sweden (ULSAM) AD
CTR		 0.18
0.18		 0.82
0.82		 2 (0.024)
14 (0.036)		 25 (0.305)
113 (0.294)		 55 (0.671)
258 (0.670)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs1019731 Sweden (ULSAM) AD
CTR		 0.20
0.15		 0.80
0.85		 6 (0.073)
9 (0.023)		 20 (0.244)
100 (0.260)		 56 (0.683)
275 (0.716)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Caucasian
rs2033178 Sweden (ULSAM) AD
CTR		 0.07
0.05		 0.93
0.95		 0 (0.000)
3 (0.008)		 11 (0.131)
33 (0.086)		 73 (0.869)
347 (0.906)
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AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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