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 Chromosome 2: Location of published AD candidate genes
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Chromosome: 2   (1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
    Implied AD Linkage Region (Summary of Linkage Studies)
    Top Results Gene (View Top Results Methods)
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AlzGene Top Results
*New* Top Results Details
1. APOE_e2/3/4
2. CLU
3. PICALM
4. EXOC3L2
5. BIN1
6. CR1
7. SORL1
8. GWA_14q32.13
9. TNK1
10. ACE   
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AlzGene Stats
Studies: 1360
Genes: 664
Polymorphisms: 2861
Meta-analyses: 303
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TARDBP CR1 NGF AGT HSPG2 USF1 CFH PCSK9 HMGCS2 APOA2 APOA1BP FDPS PMVK PRKAB2 POU2F1 LMNA FAM63A CTSS PSEN2 SORT1 CSF1 GBA F11R RGS4 PTGS2 DHCR24 NTRK1 TNFRSF14 DVL1 TNFRSF1B IL10 ECE1 IRF6 CAMK1G HSD11B1 TNFRSF4 GMEB1 GSTM4 GSTM3 PRDX6 COG2 APH1A MTR TP73 LCK CLCNKB TNFRSF8 GBP2 COL11A1 FCER1G RXRG GSTM1 SOAT1 CHRNB2 CRP REN LRP8 NCSTN MTHFR HTR6 PARP1 BIN1 LRP2 LHCGR IRS1 NEUROD1 HK2 SOS1 GRB14 EIF2AK2 TRAK2 NDUFS1 CASP8 TANK APOB ABCA12 ABCG5 IL1RN EFEMP1 SLC11A1 IL1B IL1A DRD3 SST CAV3 APOD RFTN1 OGG1 GSK3B SLC2A2 TGM4 AHSG PPARG CCR5 CCR2 BCHE TF MME LRAT CASP6 RFC1 CPE FABP2 GC PPARGC1A SORCS2 ART3 LRPAP1 UCHL1 ALB SRP72 CASP3 COL25A1 CXCL10 CSN1S1 CXCL1 IL8 APBB2 SNCA Gainsbourg EFNA5 ARSB ADRB2 PPP2R2B WWC1 (KIBRA) PRKAA1 HMGCS1 SNCAIP CRHBP PIK3R1 NRC31 NDUFS4 IL4 HMGCR CAST SLC6A3 HMMR CD14 FGF1 TBP PPARD RXRB PPP1R10 ATXN1 BAT1 NEDD9 FLOT1 GLP1R RPS6KA2 ESR1 ESR1 FYN MICB TUBB CYP39A1 APOBEC2 ACAT2 LOC651924 UBD PGBD1 F13A1 C4A C4B CFB C2 HSPA1L VEGF MICA PLG HLA TAP1 PSMB9 TAP2 LPA GLO1 FOXO3A NOTCH4 AGER SOD2 TREM2 APOM ENPP1 TNF LTA HSPA1B HSPA1A HFE PPP1R3A MAGI2 miRNA-29a/b RELN CAV1 PAX4 GRB10 GCK ADCYAP1R1 GWA_7p15.2 ABCB1 DLD PON2 GWA_7q31.1 NUDT1 SERPINE1 AHR CD36 FGL2 LAMB1 CDK5 NPY PON3 PON1 ACHE NOS3 IL6 ADAM9 ENPP2 FABP4 ADRB3 CLU NCOA2 CRH CHRNA2 CHRNA6 PLAT WRN ADRA1A NAT2 NAT1 NRG1 DPYS LPL CDKN2A SEMA4D GRIN3A PRUNE2 IL33 HSPA5 CDKN2BAS RXRA GWA_9p24.3 GOLM1 VCP FBP1 IFT74 POMT1 DFNB31 DAPK1 PTENP1 DBH OPRS1 ABCA2 NDUFA8 VLDLR TLR4 NTRK2 PSMB7 UBQLN1 APBA1 TRAF2 ABCA1 CALHM3 CALHM1 C10orf112 PITRM1 TET1 PPP1R3C CACNB2 PTPLA TACR2 TCF7L2 CXCL12 CALHM2 HK1 ADAM12 SH3PXD2A MYST4 UBE2D1 ALOX5 RASSF4 ANXA8 APBB1IP ACF ZWINT DKK1 TSPAN15 SUPV3L1 SIRT1 SGPL1 NDST2 SAR1A CYP17A1 NEUROG3 DNAJC12 EBF3 SORCS3 CAMK2G SEC24C VCL VPS26A PRG1 DNMBP ABCC2 ENTPD7 SLK NEURL WNT8B COX15 HPSE2 SFRP5 PGAM1 SLIT1 TLL2 CYP2C8 HECTD2 hCG2039140 SORCS1 ALDH18A1 LOC439999 PCGF5 GOT1 ANK3 ECHS1 SCD OAT BAG3 PNLIPRP1 MINPP1 PTEN ACTA2 LIPF KCNMA1 AP3M1 CHST3 PSAP OPTN CYP2C19 NDUFB8 CDC2 ADRA2A LRRTM3 TFAM PLCE1 SLC18A3 CHAT FAS BICC1 LIPA CH25H EGR2 PDCD11 PPP3CB ADRB1 IDE HHEX KIF11 FLJ20445 SNCG GSTO2 VR22 PLAU GSTO1 PRSS11 RTN3 PICALM DRD4 GAB2 GAL INPPL1 PDE3B ABCC8 KCNJ11 ACAD8 ABCG4 ZNF202 IL18 CNTF SORL1 FE65 APOA5 BACE1 UCP2 MAPK8IP1 FADD CHRM1 CASP4 BIRC3 CAT APOA4 APOC3 MMP3 MMP1 INS GSTP1 TPH1 BDNF TCN1 APOA1 HBG2 CTSD IGF1 CHD4 LPAR5 IFFO1 TAPBPL LRRK2 CAND1 PZP A2MP FAM113B ABCC9 GYS2 PFKM GPD1 PPP1CC LRP6 APOBEC1 C12orf41 CCNT1 ATF7 GAPDH PPM1H GNB3 PKP2P1 TNFRSF1A GRIN2B IFNG ALDH2 VDR SCARB1 C1R AVPR1A PLA2G1B M6PR NOS1 NCAPD2 SLC11A2 LRP1 TFCP2 OLR1 A2M KLF5 CDX2 ATXN8OS HTR2A SGPP1 HIF1A TMEM63C NGB POMT2 GSTZ1 TMED8 NUMB GWA_14q31.2 MTHFD1 SOS2 NPC2 GWA_14q32.13 NP ARID4A SEL1L SERPINA3 (ACT) NFKBIA FOS CTSG DLST SERPINA1 (AAT) ESR2 PCK2 ZAP128 CYP46 KNS2 PSEN1 CSK SMAD3 CYP19A1 AGC1 MEF2A IGF1R LIPC IREB2 CYP1A1 CHRNB4 CHRNA3 APH1B CHRNA7 CHRFAM7A GWA_15p21.2 ADAM10 UBE2I HMOX2 VPS35 MEFV NQO1 TMC5 HSD11B2 ERCC4 PHKG2 CETP KIF18B COX10 GRB7 CCL8 CDK5R1 GRN CCL3 GRB2 PNMT PYY CCL5 MYH8 TP53 SERPINF2 ACE FTSJ3 SLC6A4 TNK1 THRA NGFR MAPT (TAU) ADORA2B TM4SF5 MYH13 TANC2 NOS2A BLMH MPO SREBF1 TCF2 CCL2 LOC388458 TTR DSC1 MC2R BCL2 EXOC3L2 CLPTM1 APOC4 APOC1P1 BCAM CBLC GRIN3B CARD8 PVRL2 CD33 LHB LDLR GYS1 PPP2R1A AKT2 INSR LRP3 BCL3 GALP TOMM40 USF2 ERCC2 KLK1 PEN2 LIPE XRCC1 RPS15 NDUFB7 NDUFA3 CYP4F3 APOC2 NR1H2 APOC1 PIN1 GAPDHS AKAP8 NDUFS7 GNA11 ICAM1 DNM2 TGFB1 APOE APOE GWA_20q13.33 PLCG1 HNF4A PCK1 CD40 GMEB2 CHRNA4 PRNP PRND CST3 OLIG2 LSS CBS S100B DOPEY2 C21ORF55 C21ORF63 KCNJ6 DYRK1A RUNX1 NCAM2 PRSS7 SAMSN1 APP ABCG1 MCM3AP BACE2 SYN3 CECR2 PPIL2 MIF HMOX1 CYP2D6 NDUFA6 SEPT3 ACO2 COMT TCN2 MTP18 GSTT1 ADORA2A PPARA BCR TNMD PCDH11X OTC EBP TIMP1 AR MAOB MAOA HTR2C ACSL4 MT-TS2 MT-TH MT-TR MT-TK MT-TI MT-ND4L MT-NC7 MT-haplo MT-ND6 MT-ATP8 MT-TT MT-ND1 MT-TQ MT-RNR1 MT-RNR2 MT-DLOOP MT-CO3 MT-ATP6 MT-CO2 MT-ND2 MT-TG MT-ND3 MT-ND4 MT-L2 MTND5 MT-CYB MT-COI