AlzGene

Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs2471738

Polymorphism:

rs2471738 (intron 9)

Gene:

MAPT/STH (TAU; MTBT2; FTDP-17; FLJ31424; MSTD; PPND; DDPAC; MAPTL; MTBT1; STH/MAPT)

View on ALSGene View on MSGene View on PDGene View on SZGene

Protein:

microtubule-associated protein tau/saitohin (microtubule-associated protein tau; saitohin)

Chromosome:

17 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 18 April 2011 ; Because of the complete correlation between genetic markers in MAPT and STH, these two loci have been combined for display in this database

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		T-Allele (frequency)	C-Allele (frequency)	T/T (frequency)	T/C (frequency)	C/C (frequency)
Total	8	AD CTR	no data available no data available	no data available no data available	(0) (0)	(0) (0)	(0) (0)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2471738 (intron 9)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

148T->C (exon 14)
159G->A (exon 9)
227G-T (exon 14)
254G->A (exon 9)
482C->T (exon 4A)
H47Y (AflIII)
MAPT_VNTR (intron 9)
rs1078268
rs1078997
rs11867549
rs12938245 (139C->T (exon 6))
rs16940742
rs17563986
rs1864325
rs1981997
rs2258689
rs2435200
rs2435205
rs2435211
rs3744456 (MAPT_347C/G)
rs3785880
rs4792891
rs4792893
rs4792894
rs7220988
rs8078967
rs8079215
rs9891103 (IVS11+90G)

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AlzGene Stats

Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320

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The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

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An up-to-date collection of all published genetic association studies.