AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs2297480
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 Polymorphism: rs2297480
 Gene: FDPS  (FPS)  Entrez Gene
 Protein: farnesyl diphosphate synthase   ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
A-Allele
(frequency)
C/C
(frequency)
C/A
(frequency)
A/A
(frequency)
 Caucasian 6 AD
CTR
0.22
0.23
0.78
0.77
69 (0.044)
69 (0.056)
555 (0.354)
433 (0.352)
942 (0.602)
728 (0.592)
Total 6 AD
CTR
0.22
0.23
0.78
0.77
69 (0.044)
69 (0.056)
555 (0.354)
433 (0.352)
942 (0.602)
728 (0.592)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs2297480

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs4971072

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AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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The PDGene database is supported by a grant from The Michael J. Fox Foundation in partnership with the Alzheimer Research Forum.

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The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
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An up-to-date collection of all published genetic association studies.