AlzGene - Meta-Analysis of All Published AD Association Studies (Case-Control Only) rs11244787
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 Polymorphism: rs11244787
 Gene: ADAM12  (MCMP; MLTN; MLTNA; MCMPMltna)  Entrez Gene    View on SZGene
 Protein: ADAM metallopeptidase domain 12  (meltrin alpha; a disintegrin and metalloproteinase domain 12)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian 5 AD
CTR
0.13
0.13
0.87
0.87
46 (0.016)
63 (0.024)
667 (0.236)
544 (0.210)
2113 (0.748)
1978 (0.765)
Total 5 AD
CTR
0.13
0.13
0.87
0.87
46 (0.016)
63 (0.024)
667 (0.236)
544 (0.210)
2113 (0.748)
1978 (0.765)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs11244787

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

ADAM12_Exon 19S
ADAM12_Intron11delT
ADAM12_Intron11G > A
rs1011835
rs1037804
rs10751538
rs1106955
rs1152653
rs1152654
rs1152655
rs1152656
rs12415903
rs12415953
rs1278260
rs1278265
rs1278273
rs1278278
rs1278279
rs1278280
rs1278281
rs1278282
rs1278305
rs1278319
rs1278341
rs1278390
rs1466356
rs1466360
rs1676724
rs2126744
rs2279090
rs2279091
rs2279755
rs2290841
rs2290842
rs2290844
rs2290845
rs2292692
rs2366705
rs3740199
rs3758419
rs3781001
rs3781002
rs3781013
rs3781030
rs4732
rs6693
rs728104
rs7911793
rs7913591
rs7916918
rs7922601
rs872328
rs873957

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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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An up-to-date collection of all published genetic association studies.