AlzGene - Polymorphism Details
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 Study: Ma, 2009
 Gene: ESR1  (ER; ESR; Era; ESRA; NR3A1; DKFZp686N23123)  Entrez Gene    View on MSGene   View on PDGene   View on SZGene
 Protein: estrogen receptor 1   ProteinLink
 Chromosome: 6   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 16

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   P-Allele p-Allele P/P
(frequency)		 P/p
(frequency)		 p/p
(frequency)
 Asian
rs2234693 (PvuII) China AD
CTR		 0.37
0.41		 0.63
0.59		 24 (0.110)
34 (0.158)		 113 (0.516)
110 (0.512)		 82 (0.374)
71 (0.330)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   X-Allele x-Allele X/X
(frequency)		 X/x
(frequency)		 x/x
(frequency)
 Asian
rs9340799 (XbaI) China AD
CTR		 0.28
0.31		 0.72
0.69		 21 (0.092)
22 (0.094)		 84 (0.368)
99 (0.423)		 123 (0.539)
113 (0.483)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele G-Allele T/T
(frequency)		 T/G
(frequency)		 G/G
(frequency)
 Asian
rs1514348 China AD
CTR		 0.54
0.49		 0.46
0.51		 60 (0.265)
64 (0.275)		 123 (0.544)
102 (0.438)		 43 (0.190)
67 (0.288)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele C-Allele G/G
(frequency)		 G/C
(frequency)		 C/C
(frequency)
 Asian
rs1801132 (ESR1 975) China AD
CTR		 -
-		 -
-		 0 (-)
0 (-)		 0 (-)
0 (-)		 0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs1884151 China AD
CTR		 0.43
0.43		 0.57
0.57		 40 (0.189)
41 (0.190)		 102 (0.481)
103 (0.477)		 70 (0.330)
72 (0.333)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Asian
rs2077647 (ESR1 30) China AD
CTR		 0.36
0.36		 0.64
0.64		 29 (0.131)
30 (0.138)		 102 (0.462)
98 (0.450)		 90 (0.407)
90 (0.413)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs2179922 China AD
CTR		 0.32
0.35		 0.68
0.65		 24 (0.112)
25 (0.114)		 90 (0.421)
102 (0.464)		 100 (0.467)
93 (0.423)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs2347867 China AD
CTR		 0.29
0.19		 0.71
0.81		 14 (0.061)
10 (0.043)		 103 (0.450)
69 (0.299)		 112 (0.489)
152 (0.658)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs3020364 China AD
CTR		 0.36
0.31		 0.64
0.69		 30 (0.129)
22 (0.093)		 109 (0.468)
100 (0.424)		 94 (0.403)
114 (0.483)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs3020407 China AD
CTR		 0.41
0.34		 0.59
0.66		 36 (0.157)
22 (0.095)		 118 (0.513)
113 (0.489)		 76 (0.330)
96 (0.416)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Asian
rs3798575 China AD
CTR		 0.41
0.41		 0.59
0.59		 37 (0.175)
39 (0.176)		 98 (0.462)
105 (0.473)		 77 (0.363)
78 (0.351)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Asian
rs3853248 China AD
CTR		 0.30
0.33		 0.70
0.67		 24 (0.107)
32 (0.142)		 88 (0.393)
85 (0.378)		 112 (0.500)
108 (0.480)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Asian
rs6557171 China AD
CTR		 0.48
0.39		 0.52
0.61		 49 (0.217)
43 (0.176)		 121 (0.535)
107 (0.437)		 56 (0.248)
95 (0.388)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs827423 China AD
CTR		 0.36
0.40		 0.64
0.60		 23 (0.120)
28 (0.154)		 93 (0.484)
89 (0.489)		 76 (0.396)
65 (0.357)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   G-Allele A-Allele G/G
(frequency)		 G/A
(frequency)		 A/A
(frequency)
 Asian
rs932477 China AD
CTR		 0.30
0.31		 0.70
0.69		 14 (0.061)
15 (0.067)		 110 (0.476)
109 (0.487)		 107 (0.463)
100 (0.446)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele G-Allele A/A
(frequency)		 A/G
(frequency)		 G/G
(frequency)
 Asian
rs9397456 China AD
CTR		 0.46
0.52		 0.54
0.48		 43 (0.189)
69 (0.296)		 123 (0.539)
105 (0.451)		 62 (0.272)
59 (0.253)
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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