AlzGene - Polymorphism Details
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 Study: Szymanski, 2008
 Gene: NGB   Entrez Gene
 Protein: neuroglobin   ProteinLink
 Chromosome: 14   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 May 2009
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 4

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs10133981 USA (NIMH, NCRAD) AD
CTR
0.04
0.03
0.96
0.97
1 (0.003)
1 (0.003)
28 (0.080)
14 (0.048)
322 (0.917)
274 (0.948)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs2216089 USA (NIMH, NCRAD) AD
CTR
0.40
0.48
0.60
0.52
40 (0.195)
35 (0.243)
84 (0.410)
68 (0.472)
81 (0.395)
41 (0.285)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs3783988 USA (NIMH, NCRAD) AD
CTR
0.24
0.19
0.76
0.81
23 (0.068)
6 (0.021)
114 (0.337)
93 (0.331)
201 (0.595)
182 (0.648)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs972725 USA (NIMH, NCRAD) AD
CTR
0.16
0.23
0.84
0.77
3 (0.014)
7 (0.046)
62 (0.283)
55 (0.364)
154 (0.703)
89 (0.589)
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Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimerís disease.
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