AlzGene - Polymorphism Details
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 Study: Reiman, 2007
 Gene: TTR  (PALB; TBPA; HsT2651; TTR)  Entrez Gene    View on SZGene
 Protein: transthyretin   ProteinLink
 Chromosome: 18   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 1

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   A-Allele C-Allele A/A
(frequency)		 A/C
(frequency)		 C/C
(frequency)
 Caucasian
rs3764478 USA, Netherlands AD
CTR		 0.10
0.11		 0.90
0.89		 8 (0.010)
11 (0.021)		 154 (0.186)
93 (0.175)		 668 (0.805)
427 (0.804)
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Top Results Details
1. APOE_e2/3/4
2. BIN1
3. CLU
4. ABCA7
5. CR1
6. PICALM
7. MS4A6A
8. CD33
9. MS4A4E
10. CD2AP
AlzGene Stats
Studies: 1395
Genes: 695
Polymorphisms: 2973
Meta-analyses: 320
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The National Cell Repository for Alzheimer Disease seeks to recruit 1,000 families with two or more living brothers or sisters who have been diagnosed with late onset Alzheimer’s disease.
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