AlzGene - Polymorphism Details
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 Study: Reiman, 2007
 Gene: ADAM12  (MCMP; MLTN; MLTNA; MCMPMltna)  Entrez Gene    View on SZGene
 Protein: ADAM metallopeptidase domain 12  (meltrin alpha; a disintegrin and metalloproteinase domain 12)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 18 April 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 10

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele A-Allele T/T
(frequency)
T/A
(frequency)
A/A
(frequency)
 Caucasian
rs4732 USA, Netherlands AD
CTR
0.11
0.11
0.89
0.89
9 (0.011)
9 (0.016)
163 (0.191)
98 (0.179)
681 (0.798)
442 (0.805)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2292692 USA, Netherlands AD
CTR
0.15
0.15
0.85
0.85
20 (0.023)
14 (0.025)
214 (0.249)
141 (0.256)
624 (0.727)
395 (0.718)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs1278265 USA, Netherlands AD
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs2279090 USA, Netherlands AD
CTR
0.13
0.13
0.87
0.87
21 (0.025)
24 (0.045)
175 (0.209)
96 (0.178)
642 (0.766)
418 (0.777)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs2290842 USA, Netherlands AD
CTR
0.25
0.25
0.75
0.75
47 (0.056)
34 (0.062)
322 (0.383)
207 (0.379)
471 (0.561)
305 (0.559)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2290844 USA, Netherlands AD
CTR
0.08
0.08
0.92
0.92
8 (0.010)
7 (0.013)
121 (0.146)
75 (0.139)
700 (0.844)
458 (0.848)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele G-Allele A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian
rs1466360 USA, Netherlands AD
CTR
0.38
0.41
0.62
0.59
114 (0.133)
87 (0.158)
428 (0.498)
283 (0.513)
317 (0.369)
182 (0.330)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs1676724 USA, Netherlands AD
CTR
0.38
0.41
0.62
0.59
100 (0.121)
81 (0.155)
425 (0.514)
268 (0.511)
302 (0.365)
175 (0.334)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs728104 USA, Netherlands AD
CTR
0.18
0.19
0.82
0.81
20 (0.023)
14 (0.026)
268 (0.314)
179 (0.326)
566 (0.663)
356 (0.648)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs3740199 USA, Netherlands AD
CTR
0.45
0.43
0.55
0.57
164 (0.192)
93 (0.172)
436 (0.511)
280 (0.518)
253 (0.297)
168 (0.311)
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Genes: 695
Polymorphisms: 2973
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